Are There Any Side Effects to Using Beta-Caryophyllene?

In the past few years, there’s been a spike in interest surrounding BCP (Beta-Caryophyllene). What is it? How much do we know about it? 

We know that it’s a potent anti-inflammatory substance and provides relief for pain

It’s also been recognized for its many health benefits (including antibacterial, antimicrobial, wound healing, and neurodegenerative disease combatting properties). But, we must get to the bottom of a burning question: Are there any side effects to using this popular, natural compound?

But before we do, let’s learn a little bit about BCP.

What is Beta-Caryophyllene (BCP)?

Beta-caryophyllene straddles the line between a terpene—those aromatic compounds that give plants their distinctive scents—and a cannabinoid, similar to the active ingredients in cannabis.

But it’s not just about aroma. When BCP interacts with our body’s endocannabinoid system, it specifically targets the CB2 receptors. This is where it gets interesting: it offers a variety of health and wellness benefits because of this interaction. 

Unlike THC, another compound found in cannabis that targets both CB1 and CB2 receptors, BCP does not produce psychoactive effects. This means it doesn’t cause the sensation of being high that’s commonly associated with cannabis use. So, you get the benefits for your health and well-being without any alteration to your state of mind or consciousness.

BCP’s dual identity as both a terpene and a cannabinoid makes it a fascinating subject for exploration and further study.

BCP in Natural Compounds

BCP is found in lots of different places across nature if you know where to look. From the sharp bite of black pepper to the comforting warmth of cinnamon, BCP is present in a wide array of culinary and medicinal plants. Some of the other plants it can be found in include broccoli, hops, cloves, basil, oregano, rosemary, cinnamon, and lavender, just to name a few.  BCP is also found in cannabis, which has created comparisons with a very similar compound, CBD (Cannabidiol).

This occurrence in nature underlines BCP’s importance, not just as a flavor enhancer but as a key player in traditional herbal remedies.

Cultures around the globe have tapped into these plants for their therapeutic properties long before we knew what BCP could do.

Potential Side Effects of Using BCP

When it comes to any product, the big question on everyone’s mind is about side effects. Is this compound as safe as it smells?

The good news is that BCP, with its natural roots and specialized role in tapping into our body’s endocannabinoid system, is generally without any side effects. Since it targets action on CB2 receptors and steers clear of CB1 receptors, it can deliver its therapeutic punch without the high associated with cannabis.

That being said, even with BCP’s profile being as solid as it is, individual reactions to any compound can vary, and BCP is no exception.  

The most common side effect is mild skin irritation for those who are allergic or have sensitive skin. So, it’s always recommended to listen to your body and approach BCP supplements/oils or ointment with a bit of caution, especially if you’re just starting out or dabbling with dosage.

It’s noteworthy to mention that the FDA has recognized beta-caryophyllene with a GRAS (Generally Recognized As Safe) designation. This means that, based on extensive scientific review, BCP is considered safe for use in foods and supplements under the prescribed conditions. This endorsement not only underpins BCP’s safety but also its potential as a beneficial addition to health and wellness routines.

Now, that’s all well and good, but where’s the science that proves it’s generally safe and without side effects?

Toxicity of Beta-Caryophyllene (BCP): A Study

There have been a number of studies into the safety of BCP, and all have found no toxicity so far. In fact, a recent study explored the acute and repeated-dose oral toxicity of BCP in female Swiss mice. Even at a very high dose that would have mice swimming in a peppery sea (we’re talking up to 2000 mg/kg here), the study observed no worrying clinical signs.

Their body weight stayed steady, and appetites were unchanged. Crucial health markers across the board (oxidative stress biomarkers, bloodwork, and organ health) didn’t so much as flinch.

Translating research on animals to human terms isn’t always straightforward, but these findings certainly provide encouragement. The idea of an overdose on BCP seems more theoretical than practical. But, as mentioned before, the best approach is always moderation.

Embracing Beta-Caryophyllene

Beta-caryophyllene is a cannabinoid with plenty of health benefits and no known side effects. Recent studies have highlighted BCP’s safety profile, which is reassuring. While more research is underway to better understand it, this compound has shown enough promise to be a part of your wellness routine.


DISCLAIMER

The content presented in this blog and any linked materials are not meant to be used as medical advice. It is not a substitute for professional medical expertise or treatment. If you or any other individual has a medical concern, it is recommended to consult with a healthcare provider or seek other professional medical assistance.